The Impact of social Networking on Customer Loyalty Thesis

The Impact of social Networking on Customer Loyalty - Thesis Example This essay stresses that Facebook is one of the widely use social networking websites around the world. The number of users of social media is increasing with the passage of time however youngsters are more inclined towards using of social media than people of other ages. Moreover most of the people are logging their accounts on a daily basis and thus, it has encouraged businesses to use social media to convey their marketing messages as well. Social media websites are used for different purposes, one of them is that people do research and gather information about the products and services. Social Networking Sites are a very important part of Web 2.0. SNSs have become a powerful force in shaping public opinions on virtually every aspect of commerce. SNS imply word-of-mouth marketing, and have an increasing influence on customers’ purchase decisions and in turn affects customer loyalty. The study of this topic has been really interesting due to the image that the social media portray in the society. Although there was not so much time and mean I managed to have convenient samples for a small case study, which is thus a hindrance to generalize the result of the finding. However convenient sample could provide springboard for further research. The work could have been easier if only the questionnaire has been done based on the theory chapter. Due to some misunderstanding some theories were not letter consider as to be one hence some theories has to be included latter. So the challenge was to make sure that the new.

Movies and TV Essay Example | Topics and Well Written Essays - 1250 words

Movies and TV - Essay Example Through complex and often contradictory signs, this episode shows that people cannot change their economic, political, cultural, religious, social, and gender conditions, because they subscribe to implied stereotyped myths that simplify their lives and renders complex issues of degraded humanity and declining culture as invisible. The episode depicts the complicated signs of myths in direct and indirect manners, especially those pertaining to teaching and religious signs. People accept myths, where they are â€Å"more than true† (Seger 347). Myths â€Å"connect and speak† with many people. One of the myths in the Simpson’s episode is the myth of a great teacher (Moore 404). This myth argues that a funny and creative teacher can change his/her students’ lackadaisical attitudes and behaviors toward learning and life (Moore 404). Lisa’s teacher aims to change them to model students, but in a bad way, because she has been recruited by the Movementarian sect already. The â€Å"sign† in the episode can also be indirect and contains conflicts, because Lisa struggles with her grade-sensitive personality and the need to assert her independence against social brainwashing tactics. When she falls into the brainwashing of society, the episode underscores the futility of fighting powerful institutions. Myths are better, because they make life simple and easier to understand. Another myth being dismantled in this episode is the myth of faith in God. The episode shows signs that directly attack sects like the Movementarian that takes advantage of the weak-willed and weak-minded. It, however, draws parallel with the Catholic Church, because the latter also takes money from its members in form of donation and promotes â€Å"truths† about life and how it should be lived. The Church also uses seemingly hypnotizing, repetitive chants. The main argument of this episode is that God has been turned into a lucrative business. The hero s ymbol is also present when people idolize God, because â€Å"glamour is always vulnerable to those who love it† (Postrel 354). People want a savior, someone who is more than themselves and yet seemingly similar to themselves. The episode cautions people who easily fall into the trap of blind faith, such as when people do not even check who that man waving inside the Rolls Royce car is and if there actually is a spaceship inside the barn. With the myth of faith and the superhuman God, people are lambs that can be led astray to their misfortune and death. The Simpsons also perpetuates and questions gender roles and stereotypes. Neuhaus argues that The Simpsons presents a comparatively placid appraisal of domestic gender roles (762). On the one hand, it â€Å"playfully and humorously questions the function of the nuclear family in American society† (Neuhaus 762). Marge always forgives Homer, no matter how insensitive and irresponsible he can be as a husband and father. On the other hand, the episode also imbibes the â€Å"centrality of female domesticity to the very definition of ‘a family’ † (Neuhaus 762). Marge follows her husband’s decision, although she feels wary about it. She is still under the male grasp. The episode, however, portrays a conflicting role, when Marge escapes the Movementarian’s community and seeks help from Reverend Timothy Lovejoy. She and the Reverend save Homer

Newspaper should not be produced in U.S Research Paper

Newspaper should not be produced in U.S - Research Paper Example introduction of internet and television have greatly affected business of newspaper. People can easily find information in relation to a business proposal or advertising by browsing through internet. In this situation why one will prefer to buy newspaper. Therefore, newspaper profits are declining very rapidly. Present condition of economy proposes that newspaper should not be produced mainly in US because many audit reports have shown negative financial condition of the industry and its popularity is fading day by day. Therefore, it will be suitable to stop producing newspaper and promoting this phenomena more on the basis of internet or other electronic devices (Abbott Jez, 2010). 1.2 Reasons There are many reasons which support this idea that newspaper should not be produced in US. Some of which are described below: Affect of internet and television By 1990s till present news are made available 24 hours on television channels. Introduction of internet have opened new challenges fo r the business world. News is updated on daily basis through internet. These two mediums have reduced the usage of newspaper in many parts of the world including US. Payment circulation of newspaper has been declined as compared to the revenue collected through advertisement on internet. There has been a major shift from print media to new media. This has lead to decline in the profits of newspaper. Most of its revenue goes to electronic media (Plambeck Joseph, 2010). Global warming Reading newspaper has less affect on global warming as compared to reading news online. Creating newspaper is more overweight as compared to powering computers. If one is reading newspaper for 30 minutes, it will have less impact on global warming as compared to reading news online. Newspaper circulation falls Newspapers in US are continuously at stark, its circulation is declining very rapidly, and as compared to last year, circulation of newspaper has reduced more by 9%. In accordance to Audit Bureau o f Circulation sales of newspaper in US have dropped by 6.5% in the last six months in 2010 and weekly sales have been reduced by 8.7%. These results were generated by combining all the individual newspapers in US. Newspaper circulation was in decline since many years, but majorly it was affected by recession after 2008. The main reason for this decline is internet. Many publishers have also limited their services in relation to the delivery. In past, publishers only had to cope up with cost incurred in printing, but considering the present scenario they have to manage losses related to circulation (Liedtke Michael, 2009). Some of the details in relation to the fall of circulation are: New York Times circulation dropped to 5.2% in last year and 8.2% on weekday basis. While Los Angeles Times declined by 7.6% and 9% on weekly basis. Changes in individuals behavior People taste and preferences keeps on changing. Presently, individuals are adopting technological innovations very rapidly. Even businesses are operating through electronic media rather than considering the traditional ways. In all developed countries mainly in US people are getting addicted to internet and mobile phones. They prefer to buy online rather than visiting shopping malls. Similar to that, news on daily basis is generated either through cell phone or computer devices. In this modern world every house have internet facility, if one have facility to see the news at home, why will they prefer to

Antoine Lavoisier-Life, Contributions, and the French Revolution Research Paper

Antoine Lavoisier-Life, Contributions, and the French Revolution - Research Paper Example He studied at College Mazarin from 1754 to 1761, where he was taught several subjects, such as Botany, Mathematics, Chemistry and Astronomy. In 1771, when he was 28 years old, he married Marie-Anne Pierrette Paulze, when she was barely 13 years old. Marie-Anne also took a fancy to chemistry and assisted her husband in translating crucial English documents in French. Furthermore, she came out with a biography of Antoine Laurent Lavoisier by the name ‘Lavoisier’s memoirs’. Lavoisier’s father bought a title for him in 1772, and consequently he came into membership with a privately owned company called the Farmer’s General that collected taxes from the royal government. Subsequently, his wealth and influence amplified considerably. Since he was a member of the Gun Powder Commission, he resided in the Paris Arsenal where he built a private laboratory to investigate and analyze the results of chemical experiments which had been performed by others, and als o to carry out his own. During the year 1791, he was appointed as a Secretary of the Treasury (Scott, 2). Antoine not only came with the discovery and naming of oxygen. He also established the procedure of rusting and asserted the significance of oxygen for the survival of animals and plants by ascertaining its role in respiration. He was also one of the first people who performed some complex chemical experiments, which gave rise to stoichiometry. Furthermore, he also founded the law of conservation of mass and, with the assistance of his chemical experiments, he managed to determine that animals made use of oxygen as a respiratory gas and this gas exchange was a process, which was used to create heat, and it was also very similar to the process of burning of a candle. Other than his role as a physicist, botanist and chemist, Lavoisier also achieved a law degree, but he never practiced law formally in his life. He was a prominent member of the Ferme Generale, and was also one of th e 28th tax collectors of France. During the French Revolution, he was exposed to the ire of the French revolutionaries. Being a liberal, he had to undergo major opposition from Jean-Paul Marat who supported revolutionaries. When the French Revolution was at its peak, Jean Paul Marat pressed treason accusations against Lavoisier for selling watered-down tobacco and several other crimes. During the year 1794, the period of the â€Å"Reign of Terror’, Antoine provided help to some foreign scientists and mathematicians, for example, Joseph Lagrange, under treason (New Advent, 1). The judge presiding over the case of Lavoisier rejected the appeal to forgive Lavoisir’s life and to let him go on with his unfinished work. He said, â€Å"The Republic needs neither scientists nor chemists; the course of justice cannot be delayed.† Consequently, on 8th May, 1794 when Lavoisier was 50 years old, he was guillotined in Paris. Lavoisier’s contribution to the inception of advanced chemistry was primarily concentrated in the field of theory. He added extensions, summarized and confirmed the theories and discoveries of several of his contemporaries in England and the European Continent, particularly Henry Cavendish (1731-1810), Joseph Priestley (1733-1804) and Joseph Black (1728-1799). The consequence was that there was a new and more profound understanding of chemical processes that created the

Nazi Germany in the 1930s Essay Example for Free

Nazi Germany in the 1930s Essay Jews faced several problems that made life very difficult and strenuous during the mid-1930s. People who were Jewish were often persecuted and treated as the worst class of people when it comes to social hierarchy. Throughout this time, there were many things happening to Germany that were of and related to government, which destroyed the ability for a Jewish citizen to have a positive life. There were several hardships and problems faced by Jews regarding emigration out of Europe. Also, Jewish people during this time period suffered from government and social ridicule, losing many rights and necessities that should be given to every human being upon birth. During the mid-1930s, Germany tried to persecute Jews by forcing their emigration from the country. This was caused by the anti-Semitic legislation in Germany. Jews were not allowed to take with them any more than $4 and very few belongings. Along with that, trying to get to another country was nearly impossible. With the terrible great depression that was occurring, other countries were afraid that immigrants would threaten local job opportunities, thus emigration out of Germany was very difficult for Jews (Obstacles to Immigration). All the documents required to leave the country were also nearly impossible to obtain. Jews often called these â€Å"Bureaucratic Hurdles†. These were up to 15 documents that could include 5 visa applications, 2 local citizen sponsorships, tax and financial documents, police conduct documents and evaluations, a physical, and proof of a booked passage to the new country(Documents Required to Obtain a Visa). According to Ann Jacobson , when she emigrated out of Austria, when it became part of the Reich, her father was only allowed to take $80 and they had extreme difficulty finding all the documents required to move (â€Å"Flight From the Reich†). This was extremely fortunate for her to be able to get the opportunity to move, because for most Jews, obtaining such documents was nearly impossible. Overall, trying to emigrate out of a Nazi occupied territory in the mid-1930s was almost impossible, due to the legal and social restrictions posed by people and the government. Jewish lifestyle was often full of being discriminated against and mistreatment by non-Jewish citizens and government affiliated people during this time period. Many Jewish people lost their jobs and children were taken from schools (â€Å"Flight from the Reich†). With the little things available for Jews to take with them due to confiscation and newfound poverty, Jews were figuratively chased out of Germany by Nazis (â€Å"1938 Propaganda Poster†). Poverty is caused by lack of work, and Jews definitely were forced into poverty. An example of somebody being forced out of their job was Elisabeth Abegg. She was a teacher who was forced out of the position in 1933 for being of the Jewish religion (Rescue and Resistance 1). With no money, jobs, or hope for help from others, anybody would have struggled for shear survival. That is what these Jews were being denied during this time. They were forced out of a normal lifestyle, and constantly had to be looking over their shoulders for the government. A citizen in any country should never feel threatened or attacked by their own government. For the Jews trying to survive in this time period, the case was practically opposite. The government was brutal, and forcibly making Jewish people evacuate the country, yet made immigration to other countries nearly impossible. This is what made life so difficult for Jews during this time period. Eventually there was an establishing of the Nuremburg Laws, which caused Jews to lose citizen rights in Germany (â€Å"Jews in Nazi Germany† 1). Some people tried to resist the movement, but were quickly dealt with. In 1933, Karl Barth opposed pro-Nazis and based his opposition on his biblical theology (Rescue and Resistance 11). He was expelled from Germany for his â€Å"unruly behavior† in 1935. When people got on boats to sail to new countries, the exit of Europe did not always guarantee complete freedom from the Reich. If Jews were to get on a Germany controlled ship, they were technically on German land wherever they were. It was best to get on an American controlled ship, so that Germans had no control over what happened to it or its passengers while in operation (â€Å"Flight from the Reich†). If an emigrant was on a German controlled ship, like the St. Louis, problems could have occurred. This boat consisted to 900 or more people trying to go to Cuba. The government in Germany knew that Cuba had changed its mind about accepting these people yet they did not inform the passengers. When the boat got to Cuba, it was turned around with only 28 people admitted onto the island . The rest were sent back to Europe. Only half of those people sent back ended up surviving through the Holocaust (Voyage of the St. Louis). With the difficulty posed by the inability to obtain documents, and the process it actually took to get to a new country, emigration for Germans during this time period was seemingly impossible. Altogether, this time period was probably the most difficult time for a certain persecuted group of people to live. They were treated with utmost disrespect and extremely persecuted. Even though I am not a Jew myself, I feel extreme remorse for the Jews during this time period. Being able to relate to what these people went through is nearly impossible for anybody who would ever try to give themselves the task. These people are an example of how little wrong one must do in society to be treated in the most malicious of ways. The human race itself will always be the leading factor in the prevention of development, and this time period demonstrates this more than most others. When humans do and think like the Nazis did in the mid-1930s is when our race will reach ultimate failure. People do not deserve to be persecuted or mistreated, unless it is an earned treatment for negative behavior or acts. These Jews did nothing wrong, yet were treated worse by the Reich than any other people on the planet at the time. When looking for something to take away from this, one could take away the knowledge to know how destructive a simple persecution could become. It is not wise to single out any one group of people in any social context, due to the harmful global impacts made when this happened to the Jews. Humans are all born equally, and unfortunately are unable to treat each other as such. People should always be treated and given the title and rights they were born with. That title is a human being.

Risk Factors of Cardiovascular Drugs

Risk Factors of Cardiovascular Drugs Characteristics and risk factors of Cardiovascular Drugs induced Adverse Drug Reactions: Hospital based Active Surveillance Study. Abstract: Background: Adverse Drug Reactions (ADRs) is one of the major drug-related problems in hospitalized patients. Several studies report the incidence various from 10 50% of all hospital admissions due to ADRs and no recent data available on the safety of cardiovascular drug from India. Aim: This study aims 1). To estimate incidence and characteristics of ADRs due to cardiovascular drugs in patients admitted in cardiology unit of a tertiary care teaching hospital. 2) To identify the risk factors for ADRs in hospitalized patients treated with cardiovascular drugs. Methods: A prospective active surveillance study was carried out in the cardiology department of a south Indian tertiary care teaching hospital for eight months. Population averaged Poisson regression [Generalized Estimating Equation (GEE)] models was used to estimate the adjusted relative risk associated with ADR. Results: The overall incidence of cardiovascular drug induced ADRs was 31.8%. A total of 757 patients treated cardiovascular medications. Of which 241 patients (31.8%) including 122 (16.1%) females and 119 (15.7%) males reported at least one ADR. Aspirin produced the highest number of ADRs (150; 38.7%) followed by Heparin (45; 11.6%), Atorvastatin (24; 6.2%) and Ramipril (24; 6.2%). The causality assessment reveals that 85.3% of ADRs were probable in nature. GEE was used to estimate the adjusted relative risk of each covariate associated with ADRs. The predictors of ADRs identified were: female gender, age > 60 years, multiple drug therapy (p= 0.0231) and concurrent diseases like diabetes, drugs like Heparin (RR-2.90, 95% CI 2.22-3.8) and Enalapril (RR-1.95, 95% CI 1.34-2.83). Conclusion: The incidence of cardiovascular ADRs was 31.8%. The most common drugs causing ADRs were the anti- platelet and anticoagulant class of drugs. Female gender, age > 60 years, multiple drug therapy, concurrent illness and certain drugs like heparin were identified as potential predictors for adverse reactions. Keywords: adverse drug reactions, hospitalized patients, cardiovascular drugs, pharmacovigilance, Risk factors Key Messages: This study reports the risk factors for adverse reactions to cardiovascular drugs from an Indian clinical setting. The incidence of cardiovascular drugs induced ADRs was 31.8%, which is higher than many reported studies. Anti-platelet and anticoagulant drugs were commonly associated with ADRs in the study population. Introduction: Adverse Drug Reactions (ADRs) is one of the major drug-related problems in hospitalized patients. ADRs are one of the major drug-related problems, resulting in increased morbidity and mortality and healthcare costs.[1-3]The WHO defines an ADR as a response to a drug that is noxious and unintended and occurs at doses normally used in man for the prophylaxis, diagnosis or therapy of disease, or for modification of physiological function.[4] The prevalence of cardiovascular diseases (CVDs) has increased in recent years and it has been estimated that CVDs are the most common cause of death.[5] Reports on drug related problems including adverse drug reactions associated with cardiovascular pharmacotherapy are available.[6-10]Studies report that cardiovascular drugs may account for 10 to 50% of all hospital admissions due to ADRs.[11-13] There are reports of serious adverse drug events with cardiovascular drugs.[14]Continuous monitoring of ADRs are important in patients treated with cardiovascular drugs since, these patients who need multiple drug therapies to treat their comorbid conditions and other related risks[15] Various methods are used to detect ADRs in hospitalized patients.[16] Analyzing the adverse reaction data in relation to the presence of risk factors provide the link between the ADRs and the associated factors. Such analysis might help to identify patients who are at increased risk for the adverse reaction and therefore employing suitable monitoring and the preventive procedure is possible.[17] Reports are available on the risk factors for adverse reactions.[18-20] Studies have shown that the cardiovascular drugs are most common cause of ADRs.[6,21]A university hospital-based studies report 49 % ADRs are due to commonly used cardiovascular drugs (nitrates, digoxin, propranolol, heparin, warfarin, anti-hypertensive and anti-arrhythmic drugs)[22] A number of studies are available on the adverse effects of cardiovascular drugs. In the Indian context data on adverse effects of the cardiovascular drugs is not available. Therefore, the current study was planned to evaluate ADRs due to cardiovascular drugs in hospitalized patients. This study aims 1). To estimate incidence and characteristics of ADRs due to cardiovascular drugs in patients admitted in cardiology unit of a tertiary care teaching hospital. 2) To identify the risk factors for ADRs in hospitalized patients treated with cardiovascular drugs. Subjects and Methods: A prospective active surveillance study was carried out in the department of cardiology of a tertiary care teaching hospital for eight months (Feb to Sep 2009). The study protocol was reviewed and approved by the institutional ethical committee. All patients admitted to the cardiovascular units were monitored and evaluated for cardiovascular drugs induced adverse reactions. Patients who were previously treated or newly prescribed with cardiovascular drugs were monitored and followed for detecting and recording of ADRs. Adverse drug reactions were identified by conducting a daily patient charts review, patient interview, and consultations with treating physicians. In the suspected cases, past medical/medication history of patients were collected. In addition to patients medication history, information on co-morbidities was also collected. We used the WHO criteria for defining ADRs.[4] For every identified patient with ADR, two patients without ADRs were enrolled as matched controls. The information pertaining to the suspected ADRs was collected and documented in a specially designed ADR computerized documentation database for further assessment.[23] An ADR alert card was distributed to those patients who experienced severe adverse reactions to prevent further re-exposure of the suspected drug. All ADRs were reviewed and assessed by the research team. The documented ADRs were evaluated and characterized respect to patient demographics, nature of the reactions, drugs and organ system involved and outcome of the reactions. Using standard approach, the Causality, severity, preventability and the presences of predisposing factors of the reactions were assessed and reported. Patients age and sex were considered for the analysis. ADRs were classified as either Type A or Type B according to the system introduced by Rawlins and Thompson.[24] The suspected drugs were classified according to Anatomical Therapeutic Chemical (ATC) classification based on WHO-ATC Index 2009.[25]Using WHO Adverse Reaction Terminology documented ADRs were further classified into various organ system classes.[26] Management strategies employed for the ADRs were categorized as drug withdrawal, dose reduction, additional treatment for ADR and no change in a regimen without any additional treatment. Patient outcomes were reported as fatal, fully recovered, recovering and unknown. The causality of suspected ADRs was assessed using Naranjos ADR probability scale and classified into certain, probable, possible and unlikely to be drug induced depending upon the level of association.[27] The preventability of ADRs was analyzed and categorized into definitely preventable, probably preventable and not preventable using the modified criteria of Schumock and Thornton by Lau et al.[28]Using the criterion developed by Hartwig et al., for severity assessment, we assessed the suspected ADRs and classified into mild, moderate and severe reactions.[29] The onset of ADRs was assessed and classified into sub-acute, latent and acute groups.[4] Predisposing/risk factors Many patient-related factors predispose the occurrence of ADRs. The patient related factors like age, gender, multiple and inter-current disease states, and polypharmacy are considered as significant risk factor for developing ADR.[30] Patients age was categorized into 6 groups (less than 20 years, 21-30 years, 31-40 years, 41-50 years, 51-60 years, more than 60 years). Polypharmacy was categorized as minor (2-3 drugs), moderate (4-5 drugs) or major (5 drugs) based on the classification by Veehof et al.[31] Gender of the patient was also considered as a one of the predispose factor for the development of ADRs. Multiple disease state ( > 2 coded diseases) of the patient at the time of reaction also include in the analysis. The overall incidence of ADRs was calculated using the total number of in-patient episodes which resulted in ADRs in relation to the total number of in-patients followed during the study period. The length of hospital stay for each patient was collected from Hospital Patient Administrative System (HPAS) and used to compare the Length of Stay (LOS) between patients with and without ADRs. Additional hospital stay due to ADRs was assessed using the nature and clinical features of ADRs, discussion with treating medical staffs and assessment of patients medical records. Statistical analysis Descriptive statistics was used summarize the patient demographic and clinical characteristics like gender, diagnosis, a number of drug dispensed, the frequency of ADR, drugs involved, organ system involved and severity of ADRs. Mean with 95% confidence interval was used to summarize age and LOS. Chi-square test was used to find the association between age group, gender, the LOS with and without ADRs. Relative risk was used to measure the strength of association. The data were hierarchically arranged, to count the multiple ADR episodes which can occur with multiple admissions. Population averaged Poisson regression (GEE) was used to estimate the adjusted relative risk of each covariate associated with ADR.[32,33] Further compound symmetry was used to account for the within-subject correlation. All analysis was performed using SPSS for window 15 (SPSS Inc., South Asia, Bangalore). The significance level was set at P Results: A total of 757 patients (431 men and 326 women) using cardiovascular medications were intensively monitored. The mean age of the study population was 57.21  ± 14.22 years (18 -92 years). The average length of hospital stay was 10.6  ± 5.8 days. Overall, the incidence of ADRs was 31.84%. Two hundred and fourteen patients including 122 females and 119 males reported at least one ADR. Maximum of six ADRs were reported from one patient. Compared to males, females developed more of ADRs was observed more in females when (p 0.0001). The length of stay was increased due to ADR for a minimum of 3 days and a maximum of 28 days. The frequency of different age groups in patients with and without ADRs is presented in table-1. The main diagnosis of the study population is listed in table-1. Age group of less than 20 years is excluded because of lower sample size. Age group of more than 60 years had more ADRs compared to other age groups. Cardiovascular risk factors of a patient with and without ADR are shown in table-2. The most frequent system-organ class affected by ADRs was Platelet, bleeding clotting disorders (188, 48.89%), followed by metabolic and nutritional disorders (53, 13.66%) and gastrointestinal system disorders (50, 12.89%) (Table-3). The most common strategy for management of ADRs was drug withdrawal (94.3%) and dose alteration (5.4%) (Table-4). The mean length of hospital stay was 13.3 and 6.5 days for patients with and without ADR respectively. The length of stay was found to be longer in patients with ADR. Aspirin produced the highest number of reactions (150; 38.7%) followed by heparin (45; 11.6%), Atorvastatin (24; 6.2%) and Ramipril (24; 6.2%) (Table -3) with Platelet, bleeding clotting disorders (188, 48.89%). The most frequently reported reaction was bleeding (186; 47.9%) followed by gastric ulcer (52, 13.4%) (Table-3). The causality assessment of ADRs revealed that 85.31% of ADRs were classified as probable, followed by 7.99% as definite and 6.7% as possible. 64.4 % patients recovered from the ADRs and 35.6 % were recovering at the time of discharge (Table-4). The GEE analysis shows that the female, alcoholics, smokers and patients those taking more than 7 drugs had a higher risk for developing an ADR. (Table-2). Statistical analyses also revealed that patient taking Heparin (RR 2.90, 95% CI 2.22-3.80, Enalapril (RR 1.95, 95% CI 1.34-2.83), warfarin (RR 1.69, 95% CI 1.33-2.54) had a significantly increased probability of developing of ADRs (Table-5). Discussion: ADRs can significantly increase patients mortality or morbidity and consequently higher healthcare expenditure.[34] The study findings reveal that developing an ADRs in hospitalized patients substantially contribute to patients morbidity, further increasing the disease burden and cost of managing ADRs. The incidence of ADRs (31.8%) found in this study was twice higher than a previously reported systematic review of international studies (15.1%).[2] The present study showed that females experienced a higher incidence of ADRs (9.87%) when compared to males (7.23%) which are similar to the findings of previously published studies.[1,35-37]Several reasons have been put forth for this observed difference. Men and women have a different pharmacodynamic response to various drugs; which may consider as one of the factors for women to develop more number of ADRs. But in a study reported by Jose., on comparable Indian population male patients were found to have more ADRs than female population .[38] The incidence of ADRs was higher in the elderly patients (31.19%; age > 60 Years) compare to other age groups. (à Ã¢â‚¬ ¡2= 23.03, df-5, p 0.0001); this finding is similar to the results of Mohebbi et al.[19] Studies have shown that the incidence of ADRs may increase with increasing age. Again, due to multiple comorbid conditions and receive multiple drug therapy the elderly patients tend to have a higher risk for developing an ADR. In addition, older individuals undergo changes in drug responsiveness and disposition.[39] It appears that elderly patients need more attention to prevent the occurrence of ADRs. In this study, the incidence of Aspirin-induced ADRs was 38.7% (n=150); which was the highest rate compared to other cardiovascular drugs in this study. However, High rates of ADRs with streptokinase have been reported previously.[40]Studies reported a rate of amiodarone-induced ADRs as 16%, whereas in the current study it was too low at 0.5%.[41] This might be due to the lower use of amiodarone in the current study subjects. In a study conducted by Wiffen et al., investigating ADRs induced by all groups of drugs, warfarin was among the top three drugs causing ADRs.[42] In our study, the rate of ADRs attributed to warfarin was just 3.6%, whereas heparin-induced bleeding was the second highest ADR in this study population (45, 11.6%). In this study, we found central nervous and gastrointestinal systems are the most frequently affected organ system classes by ADRs. These findings were similar to the findings of a study conducted in Iran.[13]The incidence of preventable ADRs in this study (6.9%) is comparably lower than those detected in other studies.[34]This might be probably due to intensive monitoring of CCU patients in our study. The rate of serious ADRs (22.2%) detected in this study tend to be higher than other studies.[14] Population averaged Poisson regression (GEE) model showed that factors like gender and age of more than 60 years, multiple drug therapy and the presence of co-morbidity were risk factors for experiencing ADRs. The average duration of drug usage was found to be longer in patients without ADR. It appears that most of the ADRs have been noted shortly after initiating cardiovascular drugs and the incidence of ADRs in this study population was not related to the duration of usage. Similar to findings of many other studies, increasing the number of drugs led to increased frequency of ADRs. Conclusion The finding of this study indicates that cardiovascular drugs cause serious and frequent adverse reactions. The incidence of cardiovascular ADRs was 31.84%. The most common drugs causing ADRs were the anti-platelet and anticoagulant class of drugs. Female gender, age more than 60 years and use of more than 7 drugs was found to be the risk factors for developing ADRs. The identified incidence was higher than many reported studies. The current study identified the common ADRs and their predictors. Patients with identified predictors for adverse drug reactions can be intensively monitored and necessary preventive measures can be initiated if signs of reactions are observed.

Privitization Of Airports Essay -- essays research papers fc

Privatization of Airports For 51 years Bergstrom Air Force Base was home to fighter pilots, bombers, troop carriers and reconnaissance jets. It was the first port of call for President Lyndon B. Johnson on his trips home to LBJ Country aboard Air Force One, it was where Chuck Yeager, the first pilot to break the sound barrier, once brought a disabled jet to rest in an emergency landing. In September 1993, in the path of military cutbacks Bergstrom Air Force Base was closed. But the timing was fortuitous, because the closure came as the city of Austin, Texas was considering where to build a new airport. In 1993, the expected economic loss to Austin from the Bergstrom closure was estimated at $406 million a year and a loss of some 1000 jobs. But with the possibility of utilizing the prior Bergstrom Air Force Base as an airport the Austin economy was expected to have an opportunity to rebound and even improve these results from the base closure by privatizing the airport. The trend worldwide toward airport priva tization presents an exciting and dynamic opportunity for the flying public, governments, operators and investors. The overall success of privatization of airports has been seen by the sale of long-term leases for three of the largest airports in Australia for $2.6 billion. Following this success, the Government of Australia announced their plans to privatize fifteen more airports. Several Latin American airports already are in private hands. Major airports in Argentina, Chile, Colombia, Ecuador, Mexico, Peru, Uruguay and Venezuela are already concessioned or scheduled for privatization over the next two years. Smaller airports in Central America and the Caribbean also are to be privatized. In Europe, a significant number airports have been privatized and opportunities are imminent in Germany, Portugal and elsewhere. Governments in Southeast Asia, Africa, and the world over also are developing airport privatization plans. Why has this marked trend emerged and why did the city of Aus tin choose to act in this capacity? Governments in many cases do not have the financial capacity to invest in airport expansion as well as meet other needs of their citizens. They are recognizing that on one hand there are limits to their own knowledge of, and expertise, in managing airports; and, on the other, that such expertise can be provided by others with the effe... ...ith great interest in foretelling whether the actualization of Austin-Bergstrom is as much as a success in the practical as well as it appears to be in the theory. Bibliography Bibliography American Statesman, (1999). Airbase to Airport: A model transition [Online]. Available: URL: http://www.austin360.com/news/features/local/0131recycle.html [1999, January 31]. Austin360.com, (1998). Airport ¡Ã‚ ¦s neighbors hear city ¡Ã‚ ¦s noisy plans. [Online]. Available: URL: http://www.austin360.com/news/features/local/1015noise.html [1998, October 15]. National Center for Policy Analysis, (1999). Privatization trends. [Online]. Available: URL: http://www.public-policy.org/~ncpa/pd/private/priv.html [1999]. United States General Accounting Office, GAO/NSIAD-96-149 - Report to the Chairman, Subcommittee on National Security, International Affairs, and Criminal Justice, Committee on Government Reform and Oversight, House of Representatives, (1996). August 1996 MILITARY BASES - UPDATE ON THE STATUS OF BASES CLOSED IN 1988, 1991, AND 1993. [Online]. Available: URL: www.gao.gov [1996, August]. SFA Gazette, (1999). Military Base Development [Online]. Available: URL: www .sfa.com. Word Count: 2753 Privitization Of Airports Essay -- essays research papers fc Privatization of Airports For 51 years Bergstrom Air Force Base was home to fighter pilots, bombers, troop carriers and reconnaissance jets. It was the first port of call for President Lyndon B. Johnson on his trips home to LBJ Country aboard Air Force One, it was where Chuck Yeager, the first pilot to break the sound barrier, once brought a disabled jet to rest in an emergency landing. In September 1993, in the path of military cutbacks Bergstrom Air Force Base was closed. But the timing was fortuitous, because the closure came as the city of Austin, Texas was considering where to build a new airport. In 1993, the expected economic loss to Austin from the Bergstrom closure was estimated at $406 million a year and a loss of some 1000 jobs. But with the possibility of utilizing the prior Bergstrom Air Force Base as an airport the Austin economy was expected to have an opportunity to rebound and even improve these results from the base closure by privatizing the airport. The trend worldwide toward airport priva tization presents an exciting and dynamic opportunity for the flying public, governments, operators and investors. The overall success of privatization of airports has been seen by the sale of long-term leases for three of the largest airports in Australia for $2.6 billion. Following this success, the Government of Australia announced their plans to privatize fifteen more airports. Several Latin American airports already are in private hands. Major airports in Argentina, Chile, Colombia, Ecuador, Mexico, Peru, Uruguay and Venezuela are already concessioned or scheduled for privatization over the next two years. Smaller airports in Central America and the Caribbean also are to be privatized. In Europe, a significant number airports have been privatized and opportunities are imminent in Germany, Portugal and elsewhere. Governments in Southeast Asia, Africa, and the world over also are developing airport privatization plans. Why has this marked trend emerged and why did the city of Aus tin choose to act in this capacity? Governments in many cases do not have the financial capacity to invest in airport expansion as well as meet other needs of their citizens. They are recognizing that on one hand there are limits to their own knowledge of, and expertise, in managing airports; and, on the other, that such expertise can be provided by others with the effe... ...ith great interest in foretelling whether the actualization of Austin-Bergstrom is as much as a success in the practical as well as it appears to be in the theory. Bibliography Bibliography American Statesman, (1999). Airbase to Airport: A model transition [Online]. Available: URL: http://www.austin360.com/news/features/local/0131recycle.html [1999, January 31]. Austin360.com, (1998). Airport ¡Ã‚ ¦s neighbors hear city ¡Ã‚ ¦s noisy plans. [Online]. Available: URL: http://www.austin360.com/news/features/local/1015noise.html [1998, October 15]. National Center for Policy Analysis, (1999). Privatization trends. [Online]. Available: URL: http://www.public-policy.org/~ncpa/pd/private/priv.html [1999]. United States General Accounting Office, GAO/NSIAD-96-149 - Report to the Chairman, Subcommittee on National Security, International Affairs, and Criminal Justice, Committee on Government Reform and Oversight, House of Representatives, (1996). August 1996 MILITARY BASES - UPDATE ON THE STATUS OF BASES CLOSED IN 1988, 1991, AND 1993. [Online]. Available: URL: www.gao.gov [1996, August]. SFA Gazette, (1999). Military Base Development [Online]. Available: URL: www .sfa.com. Word Count: 2753